KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IQGAP2
All Species:
14.24
Human Site:
S599
Identified Species:
34.81
UniProt:
Q13576
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13576
NP_006624.2
1575
180578
S599
E
R
V
S
S
D
G
S
W
L
K
L
N
L
H
Chimpanzee
Pan troglodytes
XP_001146396
1575
180717
S599
E
R
V
S
S
D
G
S
W
L
K
L
N
L
H
Rhesus Macaque
Macaca mulatta
XP_001114017
1632
184597
F670
Q
R
P
A
D
S
A
F
W
V
Q
H
D
M
N
Dog
Lupus familis
XP_536318
1641
188145
S665
K
S
V
S
A
E
G
S
W
L
K
L
F
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3UQ44
1575
180509
S599
D
N
E
S
S
E
G
S
W
V
T
L
N
V
Q
Rat
Rattus norvegicus
NP_001101959
1657
188814
K684
A
A
G
D
N
N
S
K
W
V
K
H
W
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413959
2023
228609
E1050
A
T
G
G
N
G
S
E
W
V
K
H
W
V
R
Frog
Xenopus laevis
NP_001082588
1660
189688
L682
T
E
D
V
D
E
S
L
W
L
K
I
K
V
K
Zebra Danio
Brachydanio rerio
NP_001121812
1680
191619
S694
Q
Q
G
T
S
G
S
S
W
V
Q
H
K
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203784
771
87814
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
50.3
86.7
N.A.
88.9
58.2
N.A.
N.A.
48.7
66.6
61.4
N.A.
N.A.
N.A.
N.A.
25.2
Protein Similarity:
100
99.8
69
91.5
N.A.
95.3
74.7
N.A.
N.A.
61.5
78
75.8
N.A.
N.A.
N.A.
N.A.
38.3
P-Site Identity:
100
100
13.3
60
N.A.
46.6
13.3
N.A.
N.A.
13.3
20
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
60
80
N.A.
73.3
40
N.A.
N.A.
33.3
40
60
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
10
0
10
10
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
10
20
20
0
0
0
0
0
0
10
0
0
% D
% Glu:
20
10
10
0
0
30
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% F
% Gly:
0
0
30
10
0
20
40
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
40
0
0
20
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% I
% Lys:
10
0
0
0
0
0
0
10
0
0
60
0
20
0
30
% K
% Leu:
0
0
0
0
0
0
0
10
0
40
0
40
0
30
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
10
0
0
20
10
0
0
0
0
0
0
30
0
10
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
20
10
0
0
0
0
0
0
0
0
20
0
0
0
20
% Q
% Arg:
0
30
0
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
10
0
40
40
10
40
50
0
0
0
0
0
0
0
% S
% Thr:
10
10
0
10
0
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
30
10
0
0
0
0
0
50
0
0
0
40
0
% V
% Trp:
0
0
0
0
0
0
0
0
90
0
0
0
20
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _